Salah, 25, was presented with the trophy by the Confederation of African Football (CAF) president Ahmad at the International Conference Centre in Accra, Ghana.
Liverpool forward Mohamed Salah capped off a strong year by taking home the CAF Player of the Year Award for 2017.
Salah played a key role in Egypt's Africa Cup of Nations campaign previous year, where the North Africans reached the finals and lost to Cameroon.
Mohamed Salah impressive 2017 ensured he had a total of 700 votes while second place Saido Mane had 100 votes and Pierre-Emerick Aubameyang had just 70 votes.
Senegal's Sadio Mane was the first runner while Gabon global Aubameyang finished third.
Since his move to Liverpool from Italian side AS Roma in the summer, Salah has been a key part of the side's attempts to retain a top-four finish for the 2017-18 season - and the Champions League football that that brings with it.
"This is a dream come true for me".
Salah left Roma to join Liverpool.
Salah is the second Egyptian to win the award after Mahmoud Al Khatib in 1983. Liverpool play local rivals Everton in the FA Cup third round at on Friday (January 5).
The winger was also in remarkable touch for his country, scoring five goals in 10 matches to help his nation qualify for the 2018 FIFA World Cup in Russian Federation.