The force also said it is investigating James Toback, the film-maker who has reportedly been accused of sexual harassment by more than 200 women, including actresses Julianne Moore, Selma Blair and Rachel McAdams. She was 26 at the time.
His comment raised the prospect that Weinstein could be arrested if he returns to his native NY from Arizona, where he has been undergoing treatment at a rehabilitation centre.
New York City Chief of Detectives Robert Boyce has said that a 2010 rape allegation against Hollywood mogul Harvey Weinstein is "credible".
"We immediately contacted the district attorney in NY and we started working the case together".
"We have an actual case here".
She accepted a ride home from Weinstein and when they arrived at her apartment, de la Huerta said he insisted on joining her for a drink.
The Boardwalk Empire made the revelations in an interview with Vanity Fair.
Weinstein denies any non-consensual relations.
Weinstein is in Phoenix for treatment following his recent sex scandal, which cost him his marriage, his reputation and his seat on The Weinstein Company board.
NY abandoned it's five-year statute of limitations for rape in 2006, meaning Weinstein could be prosecuted.
De la Huerta said she was hesitant to go public with her story, but hopes her word, along with the evidence she said she's helped investigators collect, is enough to put Weinstein in jail.
Spokesperson for he U.S. Attorney's Office for the Southern District of New York, Jim Margolin, told USA TODAY Friday morning he was unable to comment.
Rebecca Curtiss, a spokesperson for A.R.T., confirmed to USA TODAY Friday that in 2015, the theater received $600,000 from an amfAR event. We are actively investigating them. We are not the target, but of course we are cooperating fully.